Abstract

The present invention relates to novel benzo[d]isothiazolic-3(2H)-one-1,1-dioxide core compounds able to effectively and selectively inhibiting the IX and XII isoforms of the enzyme carbonic anhydrase (CA), which are predominantly expressed in hypoxic and metastatic tumors.

Research Institution

Università di Pisa

TRL

N.A.

Technologies, Systems, Applications

Biomedical, New drugs development