Broad spectrum antivirals The group identified active compounds against emerging viruses (i e Zika, Dengue, SARS COV 2). Analysis of novel foods and circular economy Study the upcycling by products in insects Analysis of the influence insect derived components in the prevention of cardiovascular diseases
The research group works in: Development and use of pharmacological and biochemical in vitro models (primary cells, cell cultures, isolated tissues/organs) for: 1.Pharmacology/safety pharmacology/cardiovascular toxicology of newly synthesized compounds, extracts, or purified compounds of natural origin. 2.Recycling and valorization of agricultural and food by-products: evaluation of protective properties against cardiovascular diseases.
The research group works in the following fields: development of epigenetic and non-epigenetic modulators for the treatment of hematologic tumors. design and synthesis of inhibitors targeting enzymes of the endocannabinoid system for the development of therapeutic agents for neurodegenerative diseases and epilepsy treatment. synthesis of new pharmacological tools for the treatment of rare diseases. Design and synthesis of enzymatic inhibitors or receptor modulators for the development of new infectious agents. Green chemistry methods for the development of new neurodegeneration modulators.
Our research activity adopts a ONE HEALTH approach while applying post genomics (proteomics, metabolomics), cell biology, biochemistry, computational biochemistry and AI in Life Sciences, sustainable pharmaceuticals and circular bioeconomy.
The Biosensors and Sensors research group is dedicated to advancing point of care devices for monitoring patients with neurodegenerative diseases.
The resarch activities are dealing with high resolution electron microscopy studies on the functional morhology of eukariotic cell organelles with particular focus on cell motility and control of the cell cycle.
The research group is focused on two key areas, synthetic organic chemistry and computational chemistry, which are highly complementary and in complete synergy with each other. the research group is interested in the development of new chemical methodologies in the medicinal chemistry context and in the study of the interaction between the drug and its macromolecular target
The invention consists of a nanofunctionalized device that enables the quantitative determination of a specific biomarker, the FKBP12 protein, involved in many diseases.
The patent application protects nontoxic small molecules (glycomimetics), easily obtained from natural compounds (carbohydrates), which can be used for personalized treatment of glycan-related diseases
The present invention consists in a safety valve for use in patients with respiratory diseases characterized by severe levels of hypoxemia, with artificial airways in mechanical ventilation. In case of programmed or accidental disconnection from the circuit, prevents the "fall" of the Positive End-Expiratory Pressure (PEEP), necessary for the recruitment of alveolar areas for gas (O2, CO2) exchange.
