Regione Toscana

Tecnologie biomediche, farmaceutihe, farmacologiche

1,3-DIAZO-4-OXA-[3.3.1]- bicyclic derivatives, process for their manufacture and their use as a medicament in particular for treating diabetes

The present invention concerns the synthesis of small molecules, obtained by a totally innovative process, characterized by a stimulatory effect on the secretion of GLP-1, a gastrointestinal hormone.

2024-10-25T13:41:19+00:0020 July 2022|

Sensorized high-throughput bioreactors for imposing hydrodynamic pressure and shear stress on cell cultures

The invention relates to a sensorized high throughput bioreactor, that can be placed in series and/or parallel with similar systems, to expose cultures of the same or different cell groups to mechanical stimuli, such as hydrodynamic pressure and shear stress, simulating physiological and pathological conditions present within an organism.

2024-10-25T13:41:20+00:0020 July 2022|

High throughput bioreactor for engineering and studying the response to chemical and physical stimuli of vascular conduits

The invention relates to a sensorized high throughput bioreactor, that can be placed in series and/or parallel with similar systems, to subject vascular conduits of different sizes to chemical-physical, mechanical and electromagnetic stimuli, simulating physiological and pathological conditions present within an organism.

2024-10-25T13:41:20+00:0020 July 2022|

Method for geometric calibration of cone-beam tomography equipment and equipment implementing that method

The purpose of the present invention is to provide a method for geometric calibration of a cone-beam tomography equipment, in particular CT or pinhole-SPECT, that derives the misalignment parameters from the scan data of a generic object, thus without resorting to specific test-objects or dummies.

2024-10-25T13:41:40+00:0018 June 2021|