Precision nanomedicine: Shaping cellulose nanocrystals
The invention consists of a smart, inexpensive and biocompatible nanomaterial with custom-designed bioactivity.
Extracorporeal Clearance Precision Meter
The extracorporeal clearance precision measurement system allows clearance rate of extracorporeal treatments to be measured in real time and adjusted to patients’ needs.
Kits for modulation of anti-rejection therapies and early detection of neurodegenerative diseases
The invention consists of a nanofunctionalized device that enables the quantitative determination of a specific biomarker, the FKBP12 protein, involved in many diseases.
Carbohydrate Mimetics in Precision Medicine
The patent application protects nontoxic small molecules (glycomimetics), easily obtained from natural compounds (carbohydrates), which can be used for personalized treatment of glycan-related diseases
Pulmonary molecular oncology
The molecular Oncology Lab is focalized on single-cell high resolution transcriptomics and cell lines and murine models follow up to drug treatment
CRISPR System for Gene Editing
The invention relates to a 'Clustered Regularly Interspersed Short Palindromic Repeat (CRISPR) CRISPR associated (Cas)’ (CRISPR-Cas) system targeting a genome sequence in a eukaryotic cell, i.e. a system useful for making modifications within the cell genome.
A Method for in vitro Diagnosis of Allergy and related Device
The invention consists of a method and related device for evaluating and diagnosing allergic-type reactions in a patient by analysing in vitro impedance changes detected by contacting the patient's serum with a given allergen
CRISPR-Cas system for gene therapy
The invention refers to the use of an engineered 'Clustered Regularly Interspersed Short Palindromic Repeat (CRISPR)-CRISPR associated (Cas)’ (CRISPR-Cas) technology targeting a sequence mutated at one or more loci in the genome of a given eukaryotic cell
Antibacterial Compounds
The compounds of the present invention are pyrazole[4,3-b]pyridin-6-carboxamide derivatives characterised by direct antibacterial activity against several Gram-positive bacteria
Biomarkers for Diabetes Therapies
The present invention represents an in vitro implementable method and related kit for assessing the response to immune tolerance restoration therapy by evaluating the expression of specific microRNAs (miRNAs) as biomarkers of residual beta-cell function