Carbohydrate Mimetics in Precision Medicine
The patent application protects nontoxic small molecules (glycomimetics), easily obtained from natural compounds (carbohydrates), which can be used for personalized treatment of glycan-related diseases
Pulmonary molecular oncology
The molecular Oncology Lab is focalized on single-cell high resolution transcriptomics and cell lines and murine models follow up to drug treatment
CRISPR-Cas system for gene therapy
The invention refers to the use of an engineered 'Clustered Regularly Interspersed Short Palindromic Repeat (CRISPR)-CRISPR associated (Cas)’ (CRISPR-Cas) technology targeting a sequence mutated at one or more loci in the genome of a given eukaryotic cell
Antibacterial Compounds
The compounds of the present invention are pyrazole[4,3-b]pyridin-6-carboxamide derivatives characterised by direct antibacterial activity against several Gram-positive bacteria
Biomarkers for Diabetes Therapies
The present invention represents an in vitro implementable method and related kit for assessing the response to immune tolerance restoration therapy by evaluating the expression of specific microRNAs (miRNAs) as biomarkers of residual beta-cell function
Antiviral Compounds and Uses thereof
The invention concers compounds that act directly on the extracellular virus.
Treatment of Alkaptonuria and Tyrosinemia type 1
The invention consists of alternative compounds to nitisinone, for the treatment of both AKU and HT1.
New compounds for the treatment of acute pain
The present invention serves the development of new therapeutic strategies and new non-opioid drugs for the treatment of pain
Therapeutics for covid-19 patients
The invention concerns the use of DNA aptamers that can shield the SARS-CoV-2 binding site on the cell, and halt the cell-to-cell spreading of coronavirus.
New Dendrimeric Pyrrolidines
The invention proposes a new approach to rare genetic diseases for which no cures are available, only symptomatic treatments through the preparation of novel multivalent molecules active toward the human enzymes responsible for them