Regione Toscana

Biomedical

Method and device for the implementation of polymeric microstructures composite and not polymeric microstructures composite and not so obtained with micro and nano internal architecture called

The patented invention relates to techniques for fabricating composite polymer microstructures and not applicable to the field of Textile Engineering.

2024-10-25T13:41:19+00:0020 July 2022|

Micro-fabrication method of polymer structures for scaffolding for tissue regeneration and biosensor development

The patented invention relates to the micro-fabrication of imprinted polymeric structures with well-defined geometry for the fabrication of bioactive scaffolds. The scaffolds can be used both as substrates for the study and fabrication of functional tissue substitutes and as biosensors.

2024-10-25T13:41:19+00:0020 July 2022|

1,3-DIAZO-4-OXA-[3.3.1]- bicyclic derivatives, process for their manufacture and their use as a medicament in particular for treating diabetes

The present invention concerns the synthesis of small molecules, obtained by a totally innovative process, characterized by a stimulatory effect on the secretion of GLP-1, a gastrointestinal hormone.

2024-10-25T13:41:19+00:0020 July 2022|

Sensorized high-throughput bioreactors for imposing hydrodynamic pressure and shear stress on cell cultures

The invention relates to a sensorized high throughput bioreactor, that can be placed in series and/or parallel with similar systems, to expose cultures of the same or different cell groups to mechanical stimuli, such as hydrodynamic pressure and shear stress, simulating physiological and pathological conditions present within an organism.

2024-10-25T13:41:20+00:0020 July 2022|

High throughput bioreactor for engineering and studying the response to chemical and physical stimuli of vascular conduits

The invention relates to a sensorized high throughput bioreactor, that can be placed in series and/or parallel with similar systems, to subject vascular conduits of different sizes to chemical-physical, mechanical and electromagnetic stimuli, simulating physiological and pathological conditions present within an organism.

2024-10-25T13:41:20+00:0020 July 2022|

Method implemented by means of a computer for determining retention times and concentration values of analytes in a mixture

The present invention relates to the automation of data interpretation from a chromatography analysis, such specifically the retention times and concentration values of analytes in a mixture.

2024-10-25T13:41:22+00:0019 July 2022|

Isoindoline derivatives such as AMPK activators

The present invention relates to the development of novel isoindoline derivatives as activators of AMPK (Adenosine MonoPhosphate-activated protein Kinase), a key enzyme in cellular metabolism. The compounds, with original chemical structure, can be usefully employed for the prevention and treatment of metabolic disorders, such as type II diabetes and obesity, as well as immune-mediated inflammatory diseases and cancer.

2024-10-25T13:41:22+00:0019 July 2022|