Compounds for use in the therapeutic and preventive treatment of neurodegenerative diseases, particularly Alzheimer's disease

The object of the present invention is the design, synthesis, and pharmacological evaluation of novel diphenylmethane core molecules, capable of simultaneously promoting activation of the autophagy process and lipid catabolism, both in vitro and in vivo. Their dual activity may represent a novel approach for the treatment of neurodegenerative diseases, such as Alzheimer.

Settore:

Life sciences

Research Institution:

Università di Pisa

Publication number:

IT201900018893A1

Technologies, Systems, Applications:

Biomedical,
New drugs development

Technological Priority:

Industrial biotechnologies,
Biomedical, pharmaceutical, pharmacological technologies