BENZO[D]ISOTHIAZOL-3(2H)-ONE-1,1-DIOXIDE core derivatives and their use in the treatment of cancer

The present invention relates to novel benzo[d]isothiazolic-3(2H)-one-1,1-dioxide core compounds able to effectively and selectively inhibiting the IX and XII isoforms of the enzyme carbonic anhydrase (CA), which are predominantly expressed in hypoxic and metastatic tumors.

Settore:

Life sciences

Research Institution:

Università di Pisa

Technologies, Systems, Applications:

New drugs development,
Biomedical

Technological Priority:

Biomedical, pharmaceutical, pharmacological technologies,
Biotechnologies for health
Pubblicato il:
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